Annual report pursuant to Section 13 and 15(d)

Document and Entity Information

Document and Entity Information (USD $)
12 Months Ended
Dec. 31, 2011
Mar. 26, 2012
Jun. 30, 2011
Entity Registrant Name Synthetic Biologics, Inc.    
Entity Central Index Key 0000894158    
Current Fiscal Year End Date --12-31    
Entity Filer Category Smaller Reporting Company    
Trading Symbol syn    
Entity Common Stock, Shares Outstanding   32,701,984  
Document Type 10-K    
Amendment Flag true    
Document Period End Date Dec. 31, 2011    
Document Fiscal Period Focus FY    
Document Fiscal Year Focus 2011    
Entity Well-Known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Public Float     $ 16,266,000
Amendment Description On May 1, 2012, we were informed by Berman & Company, P.A. ("Berman & Company"), our independent registered accounting firm, that during a regular Public Company Accounting Oversight Board ("PCAOB") inspection of Berman & Company, the PCAOB issued a comment that the audit opinion included in our Annual Report on Form 10-K for the year ended December 31, 2011 was issued by a partner at Berman & Company who was not authorized under the PCAOB rules to issue the opinion or act as our named engagement partner with respect to the Form 10-K audit (or prior 2011 Form 10-Q interim reviews) after the original engagement partner rotated off the account under the Securities and Exchange Commission's independence rules as it pertains to partner rotation (S-X Rule 2-01 - Qualifications of Accountants). We believe that our previously filed financial statements for the year ended December 31, 2011 are accurate. In addition, we have not been informed by Berman & Company or the PCAOB, that our previously filed financial statements for the year ended December 31, 2011 are not accurate or otherwise invalid. As a matter of precaution the new engagement partner at Berman & Company has since: (i) taken full responsibility for the audit as the lead engagement partner on the audit, (ii) performed a detailed review of all audit procedures related to the original audit for sufficiency and (iii) reissued the audit opinion. We are filing this Annual Report on Form 10-K/A solely for the purpose of providing the reissued audit opinion and related disclosure, and subsequent event disclosure regarding the appointment of an independent, non-executive Chairman of the Board on May 10, 2012. The review performed by the new audit partner did not result in any changes to our financial statements or notes to the financial statements for the year ended December 31, 2011, other than the addition of the May 1, 2012 and May 10, 2012 disclosures in the subsequent event note to the financial statements.