Quarterly report pursuant to Section 13 or 15(d)

Stock-Based Compensation - Summary of stock option activity (Details)

v3.22.1
Stock-Based Compensation - Summary of stock option activity (Details) - USD ($)
3 Months Ended 12 Months Ended
Nov. 16, 2020
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Options, Beginning Balance   6,255,275      
Options, Granted   0      
Options, Exercised 0 0      
Options, Expired   (2,413)      
Options, Forfeited   145,417      
Options, Ending Balance       6,255,275  
Weighted Average Exercise Price, Beginning Balance   $ 1.61      
Weighted Average Exercise Price, Granted   0      
Weighted Average Exercise Price, Exercised   0      
Weighted Average Exercise Price, Expired   75.60      
Weighted Average Exercise Price, Forfeited   $ 0.36      
Weighted Average Exercise Price, Ending Balance       $ 1.61  
Aggregate Intrinsic Value, Ending Balance       $ 0  
Stock Option [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Options, Beginning Balance     3,997,418 3,997,418  
Options, Granted   0 0 2,260,000  
Options, Exercised       0  
Options, Expired       (2,143)  
Options, Forfeited   0      
Options, Ending Balance   6,107,715     3,997,418
Options, Exercisable   3,221,457      
Weighted Average Exercise Price, Beginning Balance     $ 2.35 $ 2.35  
Weighted Average Exercise Price, Granted       0.33  
Weighted Average Exercise Price, Exercised       0  
Weighted Average Exercise Price, Expired       $ 45.15  
Weighted Average Exercise Price, Forfeited   $ 0      
Weighted Average Exercise Price, Ending Balance   1.61     $ 2.35
Weighted Average Exercise Price, Exercisable   $ 2.73      
Weighted Average Remaining Contractual Life, Balance Outstanding   5 years 3 months 3 days   5 years 6 months 29 days 6 years 1 month 2 days
Weighted Average Remaining Contractual Life, Exercisable   4 years 4 months 13 days      
Aggregate Intrinsic Value, Ending Balance   $ 0     $ 0
Aggregate Intrinsic Value, Exercisable   0      
Grant date fair value of options granted   $ 0   $ 501,000  
Exercise price of options granted   $ 0   $ 0.22