Annual report pursuant to Section 13 and 15(d)

Stock-Based Compensation and Warrants - Summary of stock option activity (Details)

v3.22.0.1
Stock-Based Compensation and Warrants - Summary of stock option activity (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Options, Exercised 0    
Stock Option [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Options, Beginning Balance 3,997,418 2,502,012  
Options, Granted 2,260,000 1,540,000  
Options, Expired (2,143) (14,944)  
Options, Forfeited   (29,650)  
Options, Ending Balance 6,255,275 3,997,418 2,502,012
Options, Exercisable 2,786,934    
Weighted Average Exercise Price, Beginning Balance $ 2.35 $ 3.62  
Weighted Average Exercise Price, Granted 0.33 0.42  
Weighted Average Exercise Price, Expired 45.15 17.57  
Weighted Average Exercise Price, Forfeited   0.55  
Weighted Average Exercise Price, Ending Balance 1.61 $ 2.35 $ 3.62
Weighted Average Exercise Price, Exercisable $ 3.16    
Weighted Average Remaining Contractual Life, Balance Outstanding 5 years 6 months 29 days 6 years 1 month 2 days 6 years 6 months 3 days
Weighted Average Remaining Contractual Life, Exercisable 4 years 5 months 8 days    
Aggregate Intrinsic Value, Ending Balance $ 0 $ 0 $ 153,353
Aggregate Intrinsic Value, Exercisable 0    
Grant date fair value of options granted $ 501,000 $ 412,000  
Exercise price of options granted $ 0.22 $ 0.27