Annual report pursuant to Section 13 and 15(d)

Stock-Based Compensation and Warrants (Details 1)

v3.10.0.1
Stock-Based Compensation and Warrants (Details 1) - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Options, Exercised   (11,965)  
Stock Option [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Options, Granted 671,500 90,286  
Options, Exercised 0 (11,966)  
Options, Expired (78,667) (19,091)  
Options, Forfeited (12,927) (32,714)  
Options, Ending Balance 938,982 359,076 332,561
Options, Exercisable 221,068    
Weighted Average Exercise Price, Granted $ 0.69 $ 20.12  
Weighted Average Exercise Price, Exercised 0 13.89  
Weighted Average Exercise Price, Expired 67.02 77.46  
Weighted Average Exercise Price, Forfeited 23.72 42.21  
Weighted Average Exercise Price, Ending Balance 15.18 $ 53.93 $ 61.87
Weighted Average Exercise Price, Exercisable $ 57.61    
Weighted Average Remaining Contractual Life, Balance Outstanding 6 years 2 months 8 days 4 years 7 months 6 days 5 years 5 months 26 days
Weighted Average Remaining Contractual Life, Exercisable 4 years 4 days    
Aggregate Intrinsic Value, Exercised $ 0 $ 163,050  
Aggregate Intrinsic Value, Ending Balance 0 1,800 $ 194,355
Aggregate Intrinsic Value, Exercisable 0    
Grant date fair value of options granted $ 301,000 $ 1,164,732  
Weighted average grant date fair value $ 0.45 $ 0.37